FlowCam® Products

The FlowCam 5000's simplified design makes it accessible across industries and ensures that it is straightforward to implement sub-visible particle analysis into any lab setting. Fluid imaging microscopy is ideal for pharmaceutical and biopharmaceutical monitoring applications, process-specific monitoring applications, and research and educational institutions.

 With the FlowCam 5000 you can:

• Go beyond size and count of your particles with over 40 morphological measurements
• Experience superior image quality and image-based measurements backed by quantitative data
• Analyze tens of thousands of particles per minute
• Save time and money with our most affordable instrument to date

Now, for the first time, you can obtain LO data to meet regulatory guidelines, and verify your data with real images, all with a single instrument, and one sample run. Our new FlowCam + LO instrument combines our patented fluid imaging microscopy technology with an embedded light obscuration module to provide you with the necessary data for USP regulations.

In the FlowCam + LO, a single sample passes continuously through two flow cells. The first uses FlowCam technology to capture digital images of visible and sub-visible particles (Fig 1), and the second uses a light obscuration module to collect data for USP regulations. (Fig 2). 

Experience Nano-Flow Imaging® with exceptional sub-visible particle image clarity below 10µm. The award-winning FlowCam Nano uses oil-immersion technology to quickly and easily image, measure, analyze, and count microparticles as small as 300nm up to 10µm.

The FlowCam Nano features a patented oil-immersion, fluid imaging microscope paired with a 40X objective.

Advantages of FlowCam Nano include:

• Image and analyze particles as small as 300nm
• Distinguish protein aggregates and other particle agglomerates and single particles measuring the same size
• Verify particle size and sample uniformity
• Use morphological data to identify the structure and nature of extrinsic particles and improve product quality

The FlowCam 8000 combines digital imaging, flow cytometry, and microscopy into a single instrument. Count and analyze tens of thousands of particles per minute and see your sub-visible particles with superior image quality.

System improvements include:

• Larger field of view and faster camera provides increased data throughput
• Integrated auto-focus mechanism to simplify focusing and provide consistent, high-resolution images
• Automated self-rinsing and self-cleaning cycles to reduce cross contamination and increase flow cell longevity
• Redesigned optical path, high-powered laser and more sensitive PMTs to enhance fluorescence signal analysis
• Interchangeable quick-connect flow cell holder to streamline operation

The FlowCam® Automated Liquid Handling system integrates with the FlowCam® 8000 for uninterrupted processing of samples. The system allows up to 288 samples to be queued for unattended operation, improved repeatability, and increased productivity. FlowCam® ALH Benefits:

• Pre-analysis sample preparation can be programmed using easy-to-use graphical and menu-driven operations.
• Heating and cooling features allow sample conditioning and control of sample degradation and evaporation during the processing.
• System is self-contained to protect against outside contamination and accidental disturbance of samples. 
• Vertical architecture saves valuable bench space while a monitor provides access to current system status and review of workflows for both instruments.